Figure 4 | Scientific Reports

Figure 4

From: Allopurinol partially prevents disuse muscle atrophy in mice and humans

Figure 4

Allopurinol-treated ankle sprain patients are partially protected against unloading-induced skeletal muscle atrophy. (A) Quantification of the changes in soleus muscle volume during lower leg immobilization with a posterior ankle splint. (B) Quantification of the changes in soleus muscle CSA during lower leg immobilization with a posterior ankle splint. (C) Representative volume images after analysis and segmentation of the soleus muscle in control and allopurinol-treated subjects. R = right, L = left, A = anterior, P = posterior, T = top, B = bottom. (D) Representative magnetic resonance images of control and allopurinol-treated subjects. The soleus muscle is shown in yellow.

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