Figure 2 | Scientific Reports

Figure 2

From: Allopurinol partially prevents disuse muscle atrophy in mice and humans

Figure 2

Allopurinol-treated mice are partially protected against hindlimb unloading-induced inflammation and oxidative stress. (A) Representative western blotting of soleus proteins (full-length blots are included in supplementary information. See Supplementary Figure 2). (B) Shows plasma MDA levels measured by HPLC. (C and D) show the densitometric analysis quantified by using relative expression in arbitrary units of MnSOD (C), and p-p38 (D). (E and F) Show NF-κB p65 binding activity (E), and plasma 6-keto prostaglandin F1α (F) Determined by ELISA. Actin was used as a loading control. Data are shown as mean ± SD. C (n = 4–7), U (n = 4–6), and UA (n = 4–6).

Back to article page