Table 4 Hazard ratios (95% confidence intervals) for new-onset diabetes according to changes in BMI.

From: Impact of weight changes on the incidence of diabetes mellitus: a Korean nationwide cohort study

Group BMI changes 2002 → 2006 Incidence ratea HR (95% CI) 2002 → 2004 Incidence ratea HR (95% CI)
Unadjusted Age-, sex-adjusted MVb-adjusted Unadjusted Age-, sex-adjusted MVb-adjusted
Non-OB >−9% 2.3 0.43 (0.30–0.60) 0.52 (0.37–0.74) 0.51 (0.35–0.74) 3.4 0.60 (0.41–0.87) 0.68 (0.47–0.99) 0.73 (0.50–1.07)
−9–−6% 3.2 0.59 (0.46–0.77) 0.68 (0.52–0.88) 0.66 (0.50–0.88) 3.0 0.53 (0.39–0.72) 0.58 (0.43–0.79) 0.61 (0.44–0.84)
−6 – −3% 3.9 0.71 (0.60–0.85) 0.80 (0.67–0.96) 0.81 (0.67–0.98) 4.8 0.85 (0.72–1.00) 0.94 (0.80–1.10) 0.89 (0.75–1.07)
−3–3% 5.5 1 1 1 5.6 1 1 1
3–6% 7.2 1.31 (1.13–1.52) 1.16 (1.00–1.34) 1.17 (0.99–1.36) 5 0.89 (0.76–1.05) 0.80 (0.68–0.95) 0.78 (0.65–0.92)
6–9% 8.1 1.46 (1.20–1.78) 1.26 (1.03–1.53) 1.20 (0.97–1.48) 7.5 1.34 (1.07–1.66) 1.19 (0.95–1.48) 1.13 (0.90–1.43)
>9% 6.4 1.16 (0.89–1.51) 0.93 (0.71–1.22) 0.92 (0.70–1.23) 7.3 1.30 (0.97–1.76) 1.08 (0.80–1.45) 1.04 (0.75–1.43)
P   <0.001 <0.001 <0.001 3.4 <0.001 <0.001 0.002
OB >−9% 8.9 0.61 (0.48–0.76) 0.73 (0.59–0.92) 0.74 (0.59–0.95) 9.9 0.72 (0.53–0.99) 0.84 (0.61–1.15) 0.77 (0.54–1.09)
−9–−6% 10.7 0.73 (0.60–0.89) 0.81 (0.67–0.99) 0.83 (0.68–1.03) 11.0 0.80 (0.63–1.01) 0.91 (0.72–1.15) 0.89 (0.69–1.14)
−6–−3% 12.2 0.83 (0.72–0.96) 0.88 (0.76–1.01) 0.89 (0.77–1.04) 13.8 1.01 (0.87–1.16) 1.06 (0.92–1.23) 1.01 (0.86–1.19)
−3–3% 14.6 1 1 1 13.7 1 1 1
3–6% 15.5 1.06 (0.89–1.26) 1.02 (0.86–1.21) 1.05 (0.87–1.26) 13.5 0.98 (0.83–1.16) 0.95 (0.80–1.12) 0.93 (0.78–1.11)
6–9% 18.7 1.28 (0.99–1.65) 1.25 (0.97–1.61) 1.32 (1.01–1.73) 12.4 0.90 (0.68–1.19) 0.88 (0.66–1.16) 0.81 (0.60–1.11)
>9% 13.5 0.92 (0.61–1.40) 0.93 (0.61–1.40) 0.74 (0.45–1.19) 18.1 1.32 (0.96–1.80) 1.30 (0.95–1.78) 1.35 (0.98–1.87)
P   <0.001 <0.001 <0.001   0.074 0.328 0.466
  1. aPer 1000 person-years. bMV includes age, sex, current smoking, alcohol drinking, exercise, income, hypertension, dyslipidemia, and a family history of diabetes.