Table 3 Rate of embryo aneuploidy in monogenic disease patients.

From: Importance of embryo aneuploidy screening in preimplantation genetic diagnosis for monogenic diseases using the karyomap gene chip

Group n Euploidy n (%) Aneuploidy n (%)
Unaffected embryos 117 86 (73.5) 31 (26.5)
Affected embryos 58 49 (84.5) 9 (15.5)
Total n (%) 175 135 (77.1) 40 (22.9)
  1. This table illustrates the rate of embryo aneuploidy in the subgroup of unaffected and affected embryo diagnosed for monogenic disorder. Though there is no significant defference of aneuploidy rate between the two groups (P < 0.05 where * noted), among those embryos diagnosed as unaffected for monogenic diseases, 26.5% (31/117) of the embryos were aneuploid and could not be transferred.