Table 3 Effects of repeated administration of SSR411298 and the antidepressant fluoxetine for 33 days on chronic mild stress-induced anxiogenic-like behaviors in the mouse defense test battery.

From: The selective reversible FAAH inhibitor, SSR411298, restores the development of maladaptive behaviors to acute and chronic stress in rodents

  Non stressed control Stressed control SSR411298 (10 mg/kg, i.p.) Fluoxetine (10 mg/kg, i.p.)
Line crossings 40,9 ± 5,9 82,9 ± 6,5 50,9 ± 5,3** 52,3 ± 9,9**
Avoidances 1.3 ± 0.4 3,5 ± 0,4 1.4 ± 0,6** 0,9 ± 0,4**
Bitings 1,5 ± 0,3 2,8 ± 0,2 1,4 ± 0,5* 1,5 ± 0,3*