Effects of SSR411298 in several models of anxiety involving prior stress exposure, including (A) social defeat induced anxiogenic-like behavior in mice in the elevated plus-maze test. *P < 0.05, **P < 0.01 (vs stressed vehicle) and +P<0.05, ++P < 0.01 (vs non-stressed vehicle). N = 8–13 mice per group; (B) ultrasonic distress vocalizations emitted during three minutes by 7-day-old rat pups separated from their mother and littermates. *P < 0.05, **P < 0.01 and ***P < 0.001. N = 7–10 rat pups/group; (C) short-term memory impairment induced by inescapable stress in an object recognition task mice. **P < 0.01, ***P < 0.001, new vs familiar object. N = 10 mice per group. Data represent mean+SEM.