Table 1 Statistically significant differentially expressed mRNAs and lncRNAS number in PBMC from ALS patients, in terms of up-regulated transcripts, down-regulated transcripts and total. Counts are reported for sporadic ALS patients (SALS) and for mutated patients (FUS, TARDPB and SOD1).

From: Long non-coding and coding RNAs characterization in Peripheral Blood Mononuclear Cells and Spinal Cord from Amyotrophic Lateral Sclerosis patients

  SALS FUS TARDB SOD1
mRNAs lncRNAs mRNAs lncRNAs mRNAs lncRNAs mRNAs lncRNAs
UP-regulated 57 183 35 16 10 6 14 0
DOWN-regulated 30 110 87 5 20 9 4 2
total 87 293 122 21 30 15 18 2
  1. Transcripts were considered as differentially expressed when |log2(disease sample/healthy control)| ≥ 1 and a FDR ≤ 0.1.