Table 3 Association of the new loci with OAG and each of the endophenotypes separately.

From: Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma

Chr SNP P-value OAG (ANZRAG) P-value OAG (combined)* P-value CA P-value DA P-value VCDR P-value IOP Nearest gene
10 rs4918865^ 1.89 × 10−5 2.31 × 10−6 6.66 × 10−5 0.9062 2.10 × 10−5 0.3966 MYOF and XRCC6P1
3 rs56962872 2.91 × 10−5 3.03 × 10−7 0.000321 0.2832 0.000209 0.3793 LINC02052 and CRYGS
9 rs6478746 1.09 × 10−5 9.10 × 10−7 0.001659 0.6499 0.003575 0.03146 LOC105376277 and LMX1B
13 rs9530458 4.50 × 10−6 3.45 × 10−9 0.01305 0.2964 0.01631 0.04911 LMO7
  1. ^rs4918865 is in high LD with rs72815193, LD r2 = 0.93; *Meta-analysis of OAG in ANZRAG and NEIGHBORHOOD data; OAG, open-angle glaucoma; CA, cup area; DA, disk area; VCDR, vertical cup to disk ratio; IOP, intraocular pressure.