Figure 4 | Scientific Reports

Figure 4

From: Starfish Apaf-1 activates effector caspase-3/9 upon apoptosis of aged eggs

Figure 4

The amino acid sequence and the domain organization of sfApaf-1. (a) Amino acid sequence of sfApaf-1. The one putative nucleotide-binding site (GXXGXGK) is underlined (orange). sfApaf-1 contains three domains: CARD (red), NOD (purple), and 11 WD40 repeats (green). (b) Domain organization of sfApaf-1. The 3714 nt open reading frame (ORF) of starfish Apaf-1 encodes a 1238-aa protein with an amino terminal CARD (residues 13–90), NOD (residues 136–396), and WD40 repeat region (residues 621–1156).

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