Figure 4 | Scientific Reports

Figure 4

From: Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer

Figure 4

Carboplatin GWAS. Manhattan plots of carboplatin clearance GWAS (a) unadjusted and (b) adjusted for glomerular filtration rate; (c) LocusZoom plot for ABCC2 loci from adjusted carboplatin GWAS. The colour shading indicates the strength of LD (r2) from the reference of 1000 Genome Project (CEU samples) between the corresponding SNP and the labelled SNP, rs8187710. The red horizontal line indicates the genome-wide significance threshold of P = 5 × 10−8; the blue line is the threshold for putative association (P = 10−5).

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