Table 1 Characteristics of exenitide-loaded NPs.

From: Fc-modified exenatide-loaded nanoparticles for oral delivery to improve hypoglycemic effects in mice

Batch Copolymer type Polymer concentration Fc conjugation Particle size (nm) PDI Zeta Potential (mV) EE(%)
1 PEG5000-PLGA20000 1 mg/mL No 109 ± 6.7 0.144 −3.56 ± 2.12 83.5 ± 2.8
2 PEG5000-PLGA28000 1 mg/mL No 117 ± 7.3 0.079 −4.26 ± 1.04 59.5 ± 3.4
3 PEG5000-PLGA20000 3 mg/mL No 127 ± 5.2 0.089 −2.38 ± 1.15 62.9 ± 2.3
4 PEG5000-PLGA20000 5 mg/mL No 143 ± 4.9 0.073 −3.25 ± 2.41 52.4 ± 2.9
5 PEG5000-PLGA20000 1 mg/mL Yes 140 ± 4.2 0.156 −4.87 ± 1.52 83.5 ± 2.8
  1. Note: The particle size and PDI are detected by DLS method.