Figure 2 | Scientific Reports

Figure 2

From: Experimental infection of cattle with Mycobacterium tuberculosis isolates shows the attenuation of the human tubercle bacillus for cattle

Figure 2

Cytokine analysis of stimulated whole blood from M. tuberculosis H37Rv, M. tuberculosis BTB1558 or M. bovis AF2122/97 infected cattle. PPD-B stimulated-whole blood supernatants were assayed for IL-1β, IL-10, IL-12 (D), and TNF-α cytokine levels using a custom-designed bovine MSD. The response in the M. tuberculosis H37Rv infected cattle is shown as squares; M. tuberculosis BTB1558 is shown as triangles; and M. bovis AF2122/97 shown as circles; all groups contained 4 animals. IL-10 and IL-12 responses are reported as U/ml while IL-1β and TNF-α responses are reported in ng/ml as interpolated from the standard curves for each cytokine included on each plate. Data for each time point is presented as the mean response + SEM.

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