Table 6 Univariable and multivariable meta-regression models for the mean HCV prevalence among populations in Iran.

From: The epidemiology of hepatitis C virus in Iran: Systematic review and meta-analyses

  Number of studies Univariable analysis Multivariable analysisa
OR (95% CI) p-value AOR (95% CI) p-value
Population classification General population (low risk) 122 1 1
PWID 56 269.41 (175.01–414.72) 0.000 88.80 (52.30–150.75) 0.000
HIV patients 25 273.98 (152.38–492.64) 0.000 135.48 (72.30–253.87) 0.000
Populations at high risk of healthcare-related exposures 127 48.08 (34.26–67.46) 0.000 39.33 (25.69–60.20) 0.000
Populations at intermediate risk 70 10.10 (6.76–15.10) 0.000 4.36 (2.74–6.94) 0.000
Populations with liver-related conditions 28 16.34 (9.34–28.61) 0.000 10.24 (5.65–18.55) 0.000
Other special clinical populations 44 7.22 (4.51–11.55) 0.000 6.01 (3.61–10.02) 0.000
Study site Community 42 1 1
Blood bank 73 0.31 (0.15–0.64) 0.002 0.45 (0.7–0.77) 0.003
Prison 44 28.12 (12.6–62.71) 0.000 3.66 (2.05–6.52) 0.000
Rehab/Drop-in-center 35 48.49 (20.71–113.56) 0.000 2.26 (1.19–4.33) 0.013
Healthcare setting 256 5.72 (3.08–10.62) 0.000 0.64 (0.40–1.02) 0.063
Unspecified 22 3.74 (1.41–9.96) 0.008 1.11 (0.56–2.18) 0.766
Sampling methodology Probability-based 52 1 1
Nonprobability-based 390 1.7 (0.88–3.46) 0.114
Unspecified 30 1.81 (0.62–5.26) 0.274
Sampling size <100 144 1 1
≥100 328 0.28 (0.18–0.44) 0.000 0.70 (0.53–0.92) 0.010
Year of data collection   472 0.95 (0.90–1.00) 0.032 0.93 (0.91–0.96) 0.000
Year of publication   472 1.00 (0.91–1.02) 0.150
  1. aThe adjusted R-square for the full model was 71.74%. Abbreviations: OR= Odds ratio; AOR= Adjusted odds ratio; CI = Confidence interval; PWID = People who inject drugs.