Figure 2 | Scientific Reports

Figure 2

From: A Simple Platform for the Rapid Development of Antimicrobials

Figure 2

Bacterial and viral screening against 10,000 peptide microarrays identifies common and specific pathogen binding peptides. (A) Heat map of peptides (x-axis) that bound pathogens (y-axis). Positives peptides were defined as those with median normalized signal >2x background or >1.5x higher than the detection antibody control. For bacteria screened with the IC and CW labeling assay, positive peptides were positive in both fluorescent channels with a CW/IC ratio <5 (non-lytic peptides). Peptide intensities are colored in blue for negative and red for positive. (B) Total number of peptides positive for each pathogen evaluated. (C) Graphical representation of the number of common peptides shared amongst pathogens.

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