(A) Focal adhesion area on FLAT, FINE, and COARSE topographies. Passing from the smooth Ti to FINE and COARSE surfaces, FA area was reduced. However, upon grafting biomolecules, the dimension of the FA was increased compared to the uncoated condition of each topography. **p < 0.01 vs. uncoated condition (FLAT, FINE and COARSE, respectively). (B) Adhesion length binned by focal complexes (0–2 µm), focal adhesions (2–5 µm) and super mature adhesions (>5 µm).