Table 3 Correlation Analysis Between MBW Parameters and Quantitative Computed Tomography Assessment Parameters.

From: Lung Clearance Index and Quantitative Computed Tomography of Post-Infectious Bronchiolitis Obliterans in Infants

Quantitative CT parameters FRC before BD treatment FRC after BD treatment
r (p) r (p)
Total lung volume, ml 0.518 (0.019) 0.533 (0.015)
Normal attenuation lung volume, ml 0.656 (0.002) 0.678 (0.001)
  LCI before BD treatment LCI after BD treatment
r (p) r (p)
Air-trapping lung volume percentage, % Model 1 0.541 (0.014) 0.550 (0.012)
Model 2 0.627 (0.009) 0.498 (0.049)
Model 3 0.608 (0.016) 0.465 (0.081)
  Before BD treatment, r (p) After BD treatment, r (p)
MR1 MR2 MR1 MR2
Model 1 0.456 (0.044) 0.377 (0.101) 0.483 (0.031) 0.404 (0.077)
Model 2 0.519 (0.039) 0.400 (0.125) 0.477 (0.061) 0.439 (0.089)
Model 3 0.518 (0.048) 0.429 (0.111) 0.448 (0.094) 0.406 (0.133)
  1. Data are expressed as r (correlation coefficient) and p value adjusting for age, gender, height, and weight in model 2, and adjusting additionally for interval between infant PFT and CT in model 3.
  2. BD, bronchodilator; MBW, multiple breath washout; CT, computed tomography; FRC, functional residual capacity; LCI, lung clearance index; MR, moment ratio; PFT, pulmonary function test.