Table 1 Subject Characteristics and Quantitative Computed Tomography Assessment.

From: Lung Clearance Index and Quantitative Computed Tomography of Post-Infectious Bronchiolitis Obliterans in Infants

  Subjects (n = 20)
Age at diagnosis, month 10.9 ± 6.3
Male gender, no (%) 18 (90)
Causative pathogen of initial lower respiratory infection, no (%)
  Adenovirus 2 (10)
  Influenza 1 (5)
  Parainfluenza 4 (20)
  Respiratory syncytial virus 2 (10)
  Metapneumovirus 2 (10)
  Mycoplasma pneumoniae 3 (15)
  Other 3 (15)
  Unknown 3 (15)
Duration of recurrent airway obstruction symptoms, month 3.0 (2.0−3.8)
Interval between infant PFT and CT, day 13.5 (2.8−54.0)
Quantitative CT
Measured attenuation
  Normal lung area attenuation (HUn), HU −560 ± 68
  Air-trapping lung area attenuation (HUa), HU −759 ± 60
  Cutoff lung attenuation (HUc), HU −659 ± 60
Calculated lung volume
  Total lung volume, ml 265 ± 127
  Normal attenuation lung volume, ml 191 ± 72
  Air-trapping lung volume, ml 43 (11−120)
  Air-trapping lung volume percentage, % 22.9 ± 18
  1. Data are expressed as number (percentage), mean ± standard deviation, or median (interquartile range).
  2. PFT, infant pulmonary function test; CT, computed tomography; HU, Hounsfield units.