Figure 4: | Scientific Reports

Figure 4

From: N-terminal gelsolin fragment potentiates TRAIL mediated death in resistant hepatoma cells

Figure 4

CM and TRAIL reduce cell survival associated proteins. Analysis of survivin and the BH3 proteins (Bcl2 and Bax) in cells treated with CM, TRAIL, and CM + TRAIL. HepG2 cells exhibited a decrease in survivin and Bcl2 (panels A and B), while Bax protein level remained unchanged (panel C). In a similar experiment, Huh7 exhibited decreased survivin and Bcl2 expression when treated with both CM + TRAIL (panels D and E), while Bax level increased (panel F). Densitometric scan data is provided. Note that cropped gel images are used and the gels were run under the same experimental conditions. Each panel is representative of three independent experiments.