CM in association with TRAIL inhibits Akt and Erk activation. Akt and Erk activation was analyzed in HepG2 (panels A and C) and Huh7 (panels B and D) cells. CM was added on cells 24 hours prior to the addition of TRAIL. Densitometric scan data is provided. Each panel is representative of three independent experiments. Note that cropped gel images are used and the gels were run under the same experimental conditions.