Table 2 Evaluation of synergistic interaction between pterotilbene (PTE) and megestrol acetate (Megestrol) in variety of molar ratios on the viability of HEC-1A cells.

From: Pterostilbene, a natural phenolic compound, synergizes the antineoplastic effects of megestrol acetate in endometrial cancer

PTE: Megestrol Combination Index (CI) IC50 (μM)
ED50 ED75 ED90 PTE Megestrol
12:1 0.86 0.89 0.93 51.66 4.30
3:1 0.71 0.72 0.74 36.57 12.19
1:1 0.36 0.47 0.61 23.30 23.30
1:2 0.17 0.50 1.43 11.17 22.34
1:4 0.08 1.16 16.8 5.10 20.40