Table 1 Evaluation of synergistic interaction between pterotilbene (PTE) and megestrol acetate (Megestrol) in HEC-1A and ECC-1 cells.

From: Pterostilbene, a natural phenolic compound, synergizes the antineoplastic effects of megestrol acetate in endometrial cancer

Cells PTE: Megestrol Combination index (CI) Fold reduction (IC50)
ED50 ED75 ED90 PTE Megestrol
HEC-1A 1:1 0.36 0.47 0.61 2.75 >1000
ECC-1 1:1 0.34 0.47 0.64 2.91 >1000