Body weight of rats during experimental time. Acute weight loss was observed in all groups treated with STZ. Both mulberry leaf and glibenclamide could protect the animals from acute weight loss (6–10th weeks) to a certain extent. During the 7–8th weeks, the body weights of rats in both PCG and MTG were significantly (P < 0.01) higher than NCG. *P < 0.05 PCG compared with NCG; **P < 0.01 PCG compared with NCG; #P < 0.05 MTG compared with NCG; ##P < 0.01 MTG compared with NCG. Value = mean ± SD (N = 6).