Figure 2 | Scientific Reports

Figure 2

From: Lack of NLRP3-inflammasome leads to gut-liver axis derangement, gut dysbiosis and a worsened phenotype in a mouse model of NAFLD

Figure 2

Adipose tissue inflammation was higher in Nlrp3−/−-HFHC mice. Percentage of fat mass was increased in Nlrp3−/−-HFHC (a). MAC-2 immunohistochemistry (magnification, 40×) showed adipose tissue inflammation in Nlrp3−/−-HFHC mice (b). Gene expression of adipose tissue TNF-α (c) and MCP-1 (d) evaluated by qRT-PCR was also increased in Nlrp3−/−-HFHC mice. Mean ± SE: *p < 0.05; **p < 0.01; ***p < 0.001.

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