Table 3 Validations of the performance for the diagnosis of NASH in CHB patients by using established cutoffs.

From: Serum Monounsaturated Triacylglycerol Predicts Steatohepatitis in Patients with Non-alcoholic Fatty Liver Disease and Chronic Hepatitis B

Test Cut-offs AUROC (95% CI) Sensitivity Specificity PPV NPV LR+ LR−
TAG_1 2.1298 0.774 (0.602–0.946) 0.643 0.916 0.818 0.814 7.714 0.390
TAG_1 1.355 0.833 (0.698–0.969) 1 0.708 0.667 1 3.428 0
CK-18 (M30) 251.67 0.655 (0.466–0.843) 0.643 0.681 0.562 0.750 2.020 0.524
CK-18 (M65) 721.52 0.393 (0.203–0.583) 0.214 0.636 0.272 0.56 0.589 1.235
ALT 69.75 0.405 (0.212–0.597) 0.285 0.6 0.285 0.6 0.714 1.190
  1. CHB, active chronic hepatitis B; NASH, non-alcoholic steatohepatitis; TAG: triacylglycerol; CK-18, cytokeratin-18; ALT, alanine aminotransferase; PPV, positive predictive value; NPV, negative predictive value; LR+, positive likelihood ratio; LR−, negative likelihood ratio.