Figure 7 | Scientific Reports

Figure 7

From: HMGB1/Advanced Glycation End Products (RAGE) does not aggravate inflammation but promote endogenous neural stem cells differentiation in spinal cord injury

Figure 7

Recombinant HMGB1 protein promotes MAP-2 expressions in primary spinal neuron, but its effect can be blocked by RAGE antibody. (a) The expression of MAP-2 at 24 hours in the following groups: HMGB1; LPS and HMGB1 + anti-rage. (b) Quantitative analysis of MAP-2 expression in different groups. Values are means ± SD. &P < 0.05, HMGB1 group vs ctrl group, ^P < 0.05, HMGB1 + anti-RAGE group vs HMGB1 group.