Figure 6 | Scientific Reports

Figure 6

From: Circadian clock-dependent increase in salivary IgA secretion modulated by sympathetic receptor activation in mice

Figure 6

Effects of adrenal gland lesions on salivary IgA secretion. (a,b) Serum concentrations of corticosterone in the adrenal gland lesion (ADX) group compared to the sham-operated group for pilocarpine-only (a) and pilocarpine/NE-treated mice (b) (n = 3–6). (c,d) The rhythm of salivary IgA concentrations in the ADX group compared to that in the sham-operated mice for pilocarpine-only (c) and pilocarpine/NE-treated mice (d) (n = 3–6). (a) p = 0.0952 (Mann-Whitney test), (b) ***p < 0.001 (Student’s t-test), (c) sham, p = 0.0538 (Friedman test); ADX, p = 0.0882 (Friedman test), (d) sham, p = 0.0678 (Friedman test); ADX, **p < 0.01 (Friedman test).