Left panels A and B: Time course of changes (Δ) from baseline in diastolic blood pressure (DBP) and index of contractility (IC), respectively. Open circle (○) = men; closed diamond (♦) = women; closed square (■) = combined men and women. Right panels C and D represent mean percentage changes in DBP and IC relative to baseline. Time 0 denotes four minutes after the water drink with calculating a subsequent average over the following 30 minutes, 30 to 60 minutes, and 0 to 60 minutes post-drink, respectively, which were subtracted from each baseline level and presented as deltas. *P < 0.05 statistically significant difference over time from baseline values (right panel). All values are reported as means ± SEM.