Figure 6 | Scientific Reports

Figure 6

From: The HIV Genomic Incidence Assay Meets False Recency Rate and Mean Duration of Recency Infection Performance Standards

Figure 6

Genomic incidence assay biomarker and viral load dynamics of 21 WIHS longitudinally followed subjects. Each subject’s GSI is represented by blue filled dots and viral load by black empty dots. The GSI was measured from eight or more HIV-1 envelope gene segments (HXB2 7134-7499) from each specimen using Eq. (1). Years since infection was estimated by taking the mid-point between each subject’s last HIV negative date and first HIV positve date, and each subsequent sample collection date. The dotted black vertical line indicates ART initiation. Of 14 longitudinally sequenced subjects all except two subjects (NM1689 and SS0342) showed GSI decline over time as expected.

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