Table 2 List of strategies that combat fractional killing.

From: A dynamical framework for complex fractional killing

Strategy Experimental result Theoretical category*
Increasing drug concentration Observed CT
CIAP inhibition Observed CT
BCL inhibition Observed BG
Nutlin Observed CT
Inhibition of both CIAP and BCL Prediction AB
Caspase8 activation Prediction BG
  1. *Three categories:
  2. 1. BG- alteration of bifurcation geometry;
  3. 2. CT- alteration of cellular trajectory;
  4. 3. AB- alteration of both bifurcation geometry and cellular trajectory.