Figure 5 | Scientific Reports

Figure 5

From: The Bitter Taste Receptor TAS2R16 Achieves High Specificity and Accommodates Diverse Glycoside Ligands by using a Two-faced Binding Pocket

Figure 5

A mutation at TAS2R16 position 261 results in loss or gain of activity. (a) Activation of W261G and W261A TAS2R16 variants with a variety of ligands, activities shown as a % of their activation with wild-type TAS2R16. (b) Dose-response studies performed for wild-type (WT; solid symbols) and W261A TAS2R16 (open symbols) using the indicated ligands.