Figure 2 | Scientific Reports

Figure 2

From: In silico, in vitro, X-ray crystallography, and integrated strategies for discovering spermidine synthase inhibitors for Chagas disease

Figure 2

Results of the TcSpdSyn-ligand docking analysis. Docking poses of the top five compounds (green: docking results, pink: dcSAM). This simulation was conducted with the TcSpdSyn X-ray structure (PDB ID code: 3BWC). The docking results show that all compounds bind to the putrescine-binding site and that dcSAM binding in its own site.

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