Figure 2 | Scientific Reports

Figure 2

From: Cardiac spheroids as promising in vitro models to study the human heart microenvironment

Figure 2

Sorting of cardiomyocytes, endothelial cells and fibroblasts within cardiac spheroids. (ad) PECAM-positive ECs (blue) form a microvascular network within hCSs (a,b) and iCSs (c,d) in hanging drop cultures. Vimentin-positive iCFs (green) sort out both on the surface and within hCSs (a,b) and iCSs (c,d). Cardiac Troponin T-positive iCMs (red) are surrounded by both ECs and iCFs in hCSs (a,b) and iCSs (c,d). Scale bars: 100 μm in (a,b), 200 μm in (c,d). See also Fig. S3.

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