Figure 6 | Scientific Reports

Figure 6

From: Lack of Social Support Raises Stress Vulnerability in Rats with a History of Ancestral Stress

Figure 6

Combined ancestral and adulthood stress alter the profile of exploratory behaviour. (A–H) The paths taken by representative rats of different groups during a 20-min test session on the open field table. Note the length of path taken by MS + S-SI and MS + S-SI + T groups (G & H) that obviously are shorter than those by other groups. Home base was located at 12:00 O’clock on the table. (Bottom sub-panel-left; red dots) Representation of stops dispersion during exploration of the table top. (Bottom sub-panel-right) Rats’ speed during 20-min exploration assigned to four 5-minute intervals indicated that MS + S-SI and MS + S-SI + T groups were less motivated to explore the arena than other groups and made shorter path lengths (I) with lower speed (J) than other groups. Stop time (K) and average distance between stops (L) also indicated lower level of motor activity on the table in MS + S-SI rats compared to controls. Note the quadruple stack of plots that represent stops dispersion and distance between each stop during excursion. Stop duration is also represented by the bubble’s diameter. (M) Time spent inside or outside the home base by each group during a 20-minute session. MS + S-SI and MS + S-SI + T groups spent significantly more time inside the home base than outside, and more than any other groups.

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