Figure 5 | Scientific Reports

Figure 5

From: Lack of Social Support Raises Stress Vulnerability in Rats with a History of Ancestral Stress

Figure 5

Combined ancestral and adulthood stress induce an anxiety-like state. (A–H) Dispersion of stops and paths made by rats in open and closed arms of the elevated plus maze shows different profiles of anxiety and motivation. (G & H) The MS + S-SI and MS + S-SI + T groups displayed higher anxiety and less motivation to explore the open arms than other groups. (I & J) MS + S-SI and MS + S-SI + T groups spent longer times in closed arms compared to other groups and compared to pre-stress session. They also explored the task with lower speed (K & L) associated with shorter path length (M) and more stop times (N) compared to other experimental groups. Asterisks indicate significant differences: *p ≤ 0.05; One-Way ANOVA. Error bars show ± SEM.

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