Figure 6 | Scientific Reports

Figure 6

From: Self-diploidization of human haploid parthenogenetic embryos through the Rho pathway regulates endomitosis and failed cytokinesis

Figure 6

Self-diploidization of HPs might be result from a defect in Rho pathway activation. (A) Immunostaining of NFEs, DPs, and HPs at the first division stage, using antibodies against F-actin, p-MRLC, RhoA, and α-Tubulin; (B) Heatmap showing the relative expressions of the six core components of the Rho pathway detected by quantitative RT-PCR; (C) Quantitative RT-PCR analysis of the expression levels of the Rho pathway genes. An asterisk indicates a significant difference by a t-test (P < 0.05). NFEs: normal fertilized embryos, DPs: diploid parthenotes, HPs: haploid parthenotes, p-MRLC: serine19-phosphorylated myosin regulated light chain.

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