Figure 7 | Scientific Reports

Figure 7

From: Effects of Mesenchymal Stem Cell-Derived Exosomes on Experimental Autoimmune Uveitis

Figure 7

The effect of MSC-exo on the chemotaxis of leukocytes. IRBP-specific spleen monocytes prepared from immunized rat on day 12 post immunization were stimulated for 2 days with R16, and then added to the upper well of a microchemotaxis device and incubated in RPMI 1640 medium containing CCL2 or CCL21 with or without MSC-Exo (10 ug/ml). The cells that migrated to the lower well after 4 h were collected and the number of CD4+ (A), CD161+ (A), CD68+ (B) and Gr+ (B) cells were determined by flow cytometry. *P < 0.05.

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