Figure 2 | Scientific Reports

Figure 2

From: Image-guided transplantation of single cells in the bone marrow of live animals

Figure 2

Laser microsurgical bone removal and evaluation of tissue integrity. Images (a–d) are maximum intensity projections. Cortical bone images taken before (a) and after (b) ablation, showing the microchannel channel with the opening to the BM at the bottom. (e) Is a 3D reconstructed image of the ablated microchannel. The BM being highly vascularized, the delivery sites are selected to minimize damage to the vasculature during femtosecond laser ablation. Vasculature images taken before (c) and after (d) ablation, showing the intact blood vessels adjacent to the ablation site. White: SHG, Red: Rhodamine-6G,70kD dextran. Scale bars 50 μm.

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