Figure 3 | Scientific Reports

Figure 3

From: A-to-I editing in human miRNAs is enriched in seed sequence, influenced by sequence contexts and significantly hypoedited in glioblastoma multiforme

Figure 3

Neuron rich frontal cortex (FC) showed higher A-to-I editing in mature miRNAs than the corresponding corpus callosum (CC) of the same individuals. (A) FC showed higher A-to-I editing than CC of the same individuals (two-tailed t-test; p = 0.015). (B) Real-time PCR was done and delta Ct was plotted, ADAR2 (and not ADAR1, two-tailed t-test; p = 0.63) showed significant upregulation in FC compared to CC samples (two-tailed t-test; p = 0.008). B2M was used to normalize expression in all samples.

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