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Figure 1

From: Adaptation to dietary conditions by trehalose metabolism in Drosophila

Figure 1

Treh mutants do not cause disorganization of the optic lobe in the central nervous system. (A) Schematic diagram of the frontal view of the larval optic lobe. Lamina neuron, OPC neuroepithelial cell (OPC NE), OPC neuroblast (OPC NE), IPC neuroepithelial cell (IPC NE), and IPC neuroblast (IPC NB) are shown. (B) Treh cs1 null mutants do not cause disorganization of the optic lobe in the central nervous system in homozygotes and in trans to a chromosomal deficiency. Wandering late-third instar larvae were stained for Deadpan (Dpn, green) to label neuroblasts and for Discs large (Dlg, blue) and DE-Cadherin (DE-cad, red) to label epithelial cells. Single medial confocal sections of the optic lobe for each genotype are shown. (C) Second site mutation(s) in the lgl locus is responsible for the disorganization phenotype of Treh 18 and Treh 41 mutants in the optic lobe neuroepithelia. (D) Original P-element insertion allele of Treh 18 and Treh 41 retains second site mutation(s) in the lgl locus. Scale bars = 50 μm.

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