Figure 3 | Scientific Reports

Figure 3

From: Cnot3 enhances human embryonic cardiomyocyte proliferation by promoting cell cycle inhibitor mRNA degradation

Figure 3

Cnot3 suppresses CDKI expression by promoting the degradation of their transcripts. (a,b) The expression of CDKI mRNA (a) and CDK mRNA (b) 96 h after Cnot3 depletion in hESC-derived cardiomyocytes was determined by qPCR. β-actin was used as endogenous control and values were plotted as mean ± SEM from three independent experiments. (c) hESC-derived cardiomyocytes were treated by actinomycin D (50 µg/ml), and the amounts of CDKI mRNAs upon Cnot3 or NT silencing were determined by qPCR at the indicated time points. β-actin was used as endogenous control and values were plotted as mean ± SEM from three independent experiments.

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