Inhibition of transforming growth factor β prevented the promotion of skin wound healing by Povidone-iodine (PVI) treatment. (A) Representative photographs of wounds from rats treated with inhibitor of transform growth factor β (SB431542) or vehicle and PVI. (B) Wound contraction (%) at day 1 to 11 post-injury. *p < 0.05, **p < 0.01 vs control. Data are means ± S.D, n = 12.