Povidone-iodine (PVI) treatment enhanced cutaneous wound closure and granulation tissue formation and maturation. (A) Representative photographs of wounds from a control and PVI treated rat. (B) Wound contraction (%) at day 1 to 14 post-injury. (C) Representative micrographs of H&E stained wound sections. Red arrows indicate red blood cells. Blue arrows indicate inflammatory cells. Grey arrows indicate fibroblasts. Red asterisks indicate new blood vessels. Scale bar = 50 μm. *p < 0.05, **p < 0.01 vs control. Data are means ± S.D, n = 12.