Figure 4 | Scientific Reports

Figure 4

From: Comparative analysis of lysyl oxidase (like) family members in pulmonary fibrosis

Figure 4

LOX/L expression in human IPF lungs. (a) Masson trichrome stained histological sections of donor and IPF patient lung tissue. Nuclei appear in dark red, cytoplasm in light red and collagen in blue (scale bar = 200 \({\mu }{\rm{m}}\)). (b) Expression of LOX, LOXL1, LOXL3 and LOXL4 in IPF and donor lungs. Representative pictures of immunohistochemistry in tissue specimen of patients with IPF and transplant donors are shown. Positive cells are depicted in brown (scale bar = 50 \({\mu }{\rm{m}}\)). (c) Immunohistochemistry of LOXL2 in tissue specimen of patients with IPF and transplant donors. LOXL2 in bronchial epithelium is marked with black arrows. LOXL2 expression in hyplerplastic alveolar epithelial cells in the interstitial region and fibroblast foci are indicated by arrow heads (scale bar = 50 \({\mu }{\rm{m}}\)).

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