Two recent studies provide mechanistic insights into how LIN28A controls changes in cell fate identity, focusing on either a let-7-independent or let-7-dependent pathway of action involving LIN28A.
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Acknowledgements
The J.H.H. Laboratory is funded by Pascal and Ilana Mantoux; the Flight Attendant Medical Research Institute (FAMRI) and the EU Horizon 2020 - ERC-COG-2022 #101089297–ExUteroEmbryogenesis.
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Yilmaz, A., Gurhan, G. & Hanna, J.H. Putting together pieces of the LIN28A pathway puzzle. Nat Struct Mol Biol 31, 1313–1314 (2024). https://doi.org/10.1038/s41594-024-01380-w
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DOI: https://doi.org/10.1038/s41594-024-01380-w
