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Building up complexity in structural biology studies

Nature Structural & Molecular Biology volume 31, pages 847–848 (2024)Cite this article

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Macromolecules are involved in myriads of interactions that regulate their cellular function. While years of structural biology progress was built by reducing this complexity, a molecular understanding of biological processes requires the characterization of ever larger and more dynamic molecular assemblies. Cryo-electron microscopy is rising to this challenge.

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Acknowledgements

E.N. receives support from the National Institute of General Medical Sciences (R35GM127018), the European Research Council (ERC-2022-SYG) and the Howard Hughes Medical Institute.

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Authors and Affiliations

  1. Molecular and Cell Biology Department, University of California, Berkeley, Berkeley, CA, USA

    Eva Nogales

  2. Howard Hughes Medical Institute, Berkeley, CA, USA

    Eva Nogales

  3. Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, USA

    Eva Nogales

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  1. Eva Nogales
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Correspondence to Eva Nogales.

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The author declares no competing interests.

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Nogales, E. Building up complexity in structural biology studies. Nat Struct Mol Biol 31, 847–848 (2024). https://doi.org/10.1038/s41594-024-01324-4

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