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Inefficient splicing curbs noncoding RNA transcription

Nature Structural & Molecular Biology volume 28, pages 327–328 (2021)Cite this article

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An Author Correction to this article was published on 01 April 2021

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Pervasive genome-wide transcription initiation by RNA polymerase II (Pol II) necessitates mechanisms that restrain the quantity and length of the transcripts. A new study investigates a mechanism for inducing early transcription termination, employed primarily at genomic regions producing noncoding RNAs.

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Fig. 1: The WDR82–ZC3H4 complex curbs noncoding RNA transcription.

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Authors and Affiliations

  1. Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland

    Noa Gil

  2. Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel

    Igor Ulitsky

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  1. Noa Gil
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  2. Igor Ulitsky
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Correspondence to Noa Gil or Igor Ulitsky.

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The authors declare no competing interests.

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Gil, N., Ulitsky, I. Inefficient splicing curbs noncoding RNA transcription. Nat Struct Mol Biol 28, 327–328 (2021). https://doi.org/10.1038/s41594-021-00582-w

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