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LEUKEMOGENESIS

Seeking commonalities in fusion proteins of NUP98

Nature Structural & Molecular Biology volume 28, pages 123–124 (2021)Cite this article

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NUP98 is one of the most promiscuous fusion partners involved in leukemogenic chromosomal translocations, but the myriad of partners has long obfuscated the mechanism by which these fusion proteins drive leukemia. A new mass spectrometry–based approach has produced clues that suggest an entirely new model of leukemogenesis.

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Authors and Affiliations

  1. The University of Queensland Diamantina Institute, The University of Queensland, Woolloongabba, Queensland, Australia

    Christopher I. Slape

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  1. Christopher I. Slape
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Correspondence to Christopher I. Slape.

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The author declares no competing interests.

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Slape, C.I. Seeking commonalities in fusion proteins of NUP98. Nat Struct Mol Biol 28, 123–124 (2021). https://doi.org/10.1038/s41594-021-00558-w

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