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RNA METABOLISM

Scaling up dissection of functional RNA elements

A Publisher Correction to this article was published on 12 August 2020

This article has been updated

Translation and mRNA decay are tightly connected processes governing protein production, and their regulation involves an elaborate network of protein factors and sequence elements. A massively parallel RNA-based reporter system now reveals regulatory pathways triggered by 5′ UTR elements and allows dissection of the interplay between translation and mRNA decay.

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Fig. 1: Experimental design of the study.
Fig. 2: Biological insights gained from the study.

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Correspondence to Marc Bühler or Alex Charles Tuck.

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Bühler, M., Tuck, A.C. Scaling up dissection of functional RNA elements. Nat Struct Mol Biol 27, 771–773 (2020). https://doi.org/10.1038/s41594-020-0482-9

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