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Hooked on motility

A new cryo-EM structure of the bacterial flagellar hook, which connects the motor to the flagellar filament, reveals 11 distinctive conformations of the subunit. The cooperative dynamic switching among these states offers a dramatic extension of two-state models of protein allostery.

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Fig. 1: A view down the curved lumen of the supercoiled flagellar hook.

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Correspondence to Edward H. Egelman.

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Egelman, E.H. Hooked on motility. Nat Struct Mol Biol 26, 848–849 (2019).

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