Supplementary Figure 1: The cXR-tXA model can reproduce up-regulation of Xist in differentiating mESCs. | Nature Structural & Molecular Biology

Supplementary Figure 1: The cXR-tXA model can reproduce up-regulation of Xist in differentiating mESCs.

From: A symmetric toggle switch explains the onset of random X inactivation in different mammals

Supplementary Figure 1

Fraction of cells exhibiting mono-allelic (light grey) and bi-allelic Xist expression (dark grey) during differentiation of mESC line TX1072. Experimental data (circles) is shown together with a simulation using the parameter set that best explains the data. The number of cells analyzed is given on top. The data was pooled from 3 independent experiments.

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